From induction to movement – a detailed biophysical model of motor activation through transcranial magnetic stimulation
Project duration: May 2026 – April 2029
The TMSModel research project investigates the complex chain of effects of transcranial magnetic stimulation (TMS), from the induced electric field in the brain to the measurable response of a muscle. The aim is to develop a comprehensive biophysical model that links the activation of neural networks in the motor cortex, the transmission of nerve signals via the spinal cord and peripheral nerves, and, finally, the generation of motor-evoked potentials in the muscle. By combining experimental measurements with detailed numerical models, the aim is to gain a better mechanistic understanding of TMS and, in the long term, to lay the foundations for investigating the motor system in both health and disease.
Project partners
- Max Planck Institute for Cognitive and Neural Sciences, Leipzig; Prof. Dr. habil. Thomas Knösche
- Czech Academy of Sciences, Prague, Complex Networks and Brain Dynamics Group; Dr Vincent Chien
Contact
Prof. Dr.-Ing. Konstantin Weise
Chair of Measurement and Sensor Technology
Telephone: +49 (0)341 3076 1194
Email: konstantin(dot)weise(at)htwk-leipzig.de
